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Research Assoc II

Location:
Loch Alpine, MI
Company:
Covance

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We are looking for an Associate Scientist to join our growing team in Ann Arbor, MI.

If you have experience in developing immunohistochemistry and immunofluorescence assays and have a ASCP-HTL or ASCP-HT certification then this is the opportunity for you!

The Associate Scientist is responsible for performing immunohistochemistry procedures including: tissue dissection, routine histology, immunohistochemistry (IHC) immunocytochemistry (ICC), in-situ hybridization (ISH) and image capture of fresh, frozen and paraffin-embedded tissues and cell lines.

Duties and Responsibilities:

- Performing immunohistochemistry procedures including: tissue dissection, routine histology, immunohistochemistry (IHC), in-situ hybridization (ISH) and image capture of fresh, frozen and paraffin-embedded tissues and cell lines
- Building immunophenotyping capabilities for company
- Developing histochemical assays using various modalities including engineered antibodies, antibody mimetics and nucleic acids. Direct Immunofluorescence will be a focus.
- Performing microscopy image analysis and processing
- Identifying, develop and optimize new methods to generate reliable and reproducible data in a timely manner
- Performing detailed organization of experimental data, analyzed data for entry, and sample management
- Knowledge of inventory control and record keeping; ability to assume primary responsibility for the maintenance, transmittal and release of essential data and records as assigned.
- Skill in the safe and effective use, maintenance and calibration of a variety of automatic, semiautomatic and manual analytic instruments and devices. Knowledge of the safe and effective use of chemicals, reagents and other equipment, and the ability to demonstrate and explain their use to others. Ability to provide general oversight, guidance and direction to other staff or act as team leader a particular shift, project or activity, and ensure that protocols are followed in connection with all procedures.
- Ability to apply scientific principles and practices to new tasks and problems not previously encountered and exercise professional discretion and judgement in working with variable guidelines capable of writing and follow written procedures requiring greater specificity and interpretation, or determining when to seek further consultation.
- Ability to communicate effectively with others both verbally and through written reports, using a high degree of technical language. Ability to read and interpret communications from others.
- Ability to perform responsible decision-making in a number of areas. Ability to evaluate and validate new and existing methodologies applicable to the laboratory as well as identify problems and effectively resolve or address irregularities and discrepancies which may arise in the testing process.
- Ability to maintain the confidentiality of related materials in compliance with Company.
- Performs all other duties as assigned. May lead special projects as assigned.
EDUCATION: Bachelor’s Degree or equivalent experience in life sciences or related discipline.
- EXPERIENCE: Direct experience in developing immunohistochemistry and immunofluorescence assays
- OTHER: Strong interpersonal, organizational and project management skills required. Computer literacy required.
- Certification by the American Society of Clinical Pathologists (ASCP) as either a Histotechnologist (ASCP-HTL) OR as a Histology Technician (ASCP-HT) OR as a Medical Technologist (ASCP- MT). Or, ASCP eligible. (Preferred)
- Two (2) years of work experience in a hospital, clinical laboratory or healthcare setting as a Histotechnologist. (Preferred)
PHYSICAL DEMANDS AND WORK ENVIRONMENT
- Works in a research environment with exposure to sharps and potentially caustic chemicals and substances of unknown hazard. Must function while adhering to various PPE requirements. Noise level in laboratory is moderate.
- Specific vision abilities required by this job include close vision, color vision, depth perception, and the ability to adjust focus.

- Regularly works near animals and with serum/cells with risk of exposure to allergens, zoonotic diseases and biohazards.

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